Viagra, the well-known drug to treat impotence in men, may help in treating enlarged heart, which is accompanied by high blood pressure. That is the conclusion was drawn by researchers after a series of experiments on animals.
The next stage of research is to determine whether the revealed curative effect of Viagra is manifested in the human heart. Enlarged heart is a serious pathology, known as hypertrophy, and may lead to cardiac arrest with fatal outcome.
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Viagra drug, known in medical circle as sildenafil citrate, has stopped the hypertrophy of the heart and even it has caused the reverse reduction of the heart in mice and it has potential for further use, as it has already confirmed its safety and efficacy in the treatment of disorders of sexual function.
The ability of the drug to reduce blood pressure was detected at the first clinical trials. But the effect was not detected for a long time. Scientists are optimistic about the possibility of solving this problem, as they found mechanism of action of the drug. Sildenafil blocks the enzyme phosphodiesterase resulting in the heart muscle accumulates substance Guanosine monophosphate, which expands blood vessels and improves their work.
Development of the drug with a longer action is the task that shall be decided by the pharmacologists now.
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