Carelessness caused by
insomniainsomnia, can be corrected by using blocking certain enzymes in the hippocampus, say researchers from the University of Toronto.
Sleep deprivation leads to disruption of long-term memory in humans worldwide. Experiments on mice have shown that insomnia violates the molecular signals in the hippocampus, reducing the level of the molecule PDE4 (phosphodiesterase 4) and cyclic adenosine monophosphate. This molecule is involved in the formation of new connections of synapses required for learning.
Blocking PDE4 in mice, the scientists have increased the concentration of TSMA that counteracted the loss of memory.