An antibiotic used for acne, can be a real "revolution" in the treatment of strokes, say scientists from the United States. In a new study, they have studied the therapeutic efficacy of
minocycline in laboratory animals. It turns out that the available drug significantly reduces the level of brain damage, if it is to enter the patient immediately after a stroke.
To date the only effective medicine in the treatment of ischemic stroke is thrombolytic means tPA. However, the drug actually helps only 2% of patients, because the effect of narrowly focused. Therefore, said Dr. Cesar V. Borlongan Eugene at the University of Florida, USA, before the scientists is to create a new drug for treating victims of stroke. His new research is an important step in this direction. Together with his colleagues Dr. Borlongan found that the use of an inexpensive
antibiotic minocycline immediately after a stroke reduces the devastating impact of stroke on brain cells, in some cases by two thirds! A stroke occurs when a clot blocks a blood vessel in the brain, resulting in limited power of brain cells with their subsequent death and irreversible changes. Minocycline, introduced the patient immediately after the impact, protects the cells and reduces puffiness. Particularly effective drug protects nerve cells that process and transmit information.
Scientists do not have to create minocycline as it is already on the market, and it is used to treat acne rashes and arthritis. The use of the drug in stroke was much more effective than available in the arsenal of medical tools. In tests on laboratory animals, after a stroke in the brain of experimental there safely preserved up to 80% of nerve cells, if immediately after the attack, and then for three days, they were injected minocycline. Without such treatment there remained intact, only 40% of brain cells. According to study leader, a medicine is absolutely safe. Its action is mainly on reducing apoptosis. Also, thanks to the drug people are quickly restored after a stroke, which often leads to paralysis of the body.
Nowadays 10% of deaths occur due to stroke. Only in the UK every 5 minutes from stroke one person dies. This disease is claiming more lives than AIDS / HIV. When a stroke, a man has dying brain, which leads to short-term and long-term changes in the organism. Having studied the effects of the drug on the brain of animals, as well as isolated neurons in the laboratory, scientists are ready to begin testing of minocycline in human beings.