In search of drugs for obesity, scientists have developed a drug that not only reduces weight, but also cures diabetes and reduces cholesterol in the body. While it has been tested only on mice, the next stage - the rats and rabbits. Researchers are strongly optimistic.
Ms. Salih Wakil of the Baylor College of Medicine in Texas and Ms. Motonari Wesugi from Kyoto University in Japan claim that the drug prevents the action of genes is responsible for obesity. "We take this as a basis. This fact is interesting to us ", said Ms. Wakil.
As part of the experiment within four weeks mice were administered with the drug. As a result, their weight decreased by 12%, and the level of sugar in the blood fell by 70%.
"The drug blocked the increase in body weight of mice and blood glucose levels, and the increased accumulation of fat in the liver even in the uncontrolled consumption of food", wrote the researchers. Genetic studies have shown that the drug acts on 63 different genes.
At the same time, scientists are aware that the
drug that reduced the weight of the mice may not cause absolutely any change in weight of human being. The hormone leptin, which makes mice and rats are very thin, can not reduce the weight of an individual or cause slight changes in body weight.
The new drug also has an impact on
prostate cancer cells. The scientists say further research may help establish a link between prostate cancer and obesity.
As we have previously reported that researchers from the University of Copenhagen and Max Planck Institute in Germany, using innovative technology, have identified no less than 3,6 thousand of molecular switches in the human body. They regulate the function of 1,750 different proteins and may play a major role in aging and development of diseases such as cancer and dementia.
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