Highly demanded group of people with need for immunization by vaccine there pregnant women as the statistics confirms there are 6% of fatal cases in previous epidemic in this group. Even there is only 1% of these women calculated from the total population. It is reported by Disease Control & Prevention Centre. This group is in high risk as for the first month of the epidemic there are 4 times more pregnant women taken to hospitals in than other population, as DCPC reported.
So, there shall be 120 pregnant women at the age from 18 till 39 years old and they are in the second and third trimester of the pregnancy. All of them are volunteers and they shall take either 15mgr or 30 mgr of H1N1 vaccine made in 2009 by Dr. Sanofi Pasteur to clarify the most effective dosage. The patients shall obtain 2 injections within the period of 21 days so that the scientists and independent committee could be ensured in the safety of the vaccine. The vaccine effectiveness shall be monitored anti-body levels to the influenza virus so that the scientists could measure the vaccine effectiveness. Meanwhile, umbilical cord blood shall be read to clarify the quantity of anti-body circulates from mother to fetus via placenta.
Normally, pregnant women are excluded from clinical trials where there are no related issues to pregnancy and prevention danger for fetus including any undesirable effects. By the confirmation given by Mr. Fauci, the influenza vaccines have been utilized so far within the pregnancy period with safety first. He added that pregnant women have been vaccinated within one of any trimesters with the vaccine, and the response for all this time is positive for safety. This vaccine is lack of either thimerisol or adjuvant that boosts immune system and widely used in other vaccines.
The following medical centers are involved in this study, like Vaccine and Treatment Evaluation Units, Baylor Medicine College, Houston; Team Health Cooperative Center for Health Studies, Seattle; Saint Louis (Mo.) University; Vanderbilt University, Nashville; Duke University, Durham, N.C.; and Scott & White Memorial Polyclinic, Temple, Texas.
Tags: H1N1 vaccination, pregnant women, H1N1 vaccine, influenza virus |
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